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何承勇副教授

发布时间:2015-08-01来源:澳门新葡亰网站注册点击数:4121

何承勇CHENGYONG HE, Ph.D.

副教授/硕士生导师(澳门新葡亰网站注册)

理学博士 (澳门新葡亰网站注册)

Emailhecy@xmu.edu.cn


学术简历:

2003/09-2007/06,南京农业大学,无锡渔业学院,本科

2007/09–2009/09,厦门大学,澳门新葡亰网站注册,硕士研究生

2011/09–2012/08,Molecular and Environmental Toxicology Center, University of Wisconsin-Madison, USA国家留学基金委公派联合培养博士

2009/09–2012/12,厦门大学,澳门新葡亰网站注册生物学系,博士

2013/01–2017/07,厦门大学,公共卫生学院预防医学系,助理教授

2017/08–2018/07,厦门大学,公共卫生学院预防医学系,副教授

2018/08–至今,厦门大学,澳门新葡亰网站注册生物学系,副教授

课题组:分子毒理学

研究方向:环境毒理学;纳米毒理学


主要研究内容

1.有机污染物发育毒性及分子机制;

2.纳米材料生物安全性评价及毒性分子机制;

3.内分泌干扰物生殖发育毒性


主持和参与科研课题:

1. 厦门大学校长基金,20720180045,未折叠蛋白反应ATF4通路调控内质网自噬介导量子点肾损伤机制研究与应用,2018/1-2020/12,在研,主持

2. 国家自然科学基金青年项目,81402648,多环芳烃通过NO介导的亚硝基化影响海马神经发育的机制研究,2015/01-2017/12,已结题,主持

3. 国家重点研究计划,“肝癌高特异性近红外纳米成像探针的设计与合成”,2017-2020,参加


代表性论文

1. Chengyong He#*, Fengkai Ruan#, Shengwei Jiang#, Jie Zeng, Hanying Yin, Rong Liu, Yongxing Zhang, Laiqiang Huang, Chonggang Wang, Shaohua Ma*, Zhenghong Zuo*. Black Phosphorus Quantum Dots Cause Nephrotoxicity in Organoids, Mice and Human Cells. Small. 2020, 2001371 (IF=10.8, JCR1区).

2.  Chengyong He#Shengwei Jiang#, Haijing Jin#, Shuzhen Chen, Gan Lin, Huan Yao, Xiaoyong Wang, Peng Mi, Zhiliang Ji, Yuchun Lin*, Zhongning Lin*, Gang Liu*. Mitochondrial electron transport chain identified as a novel molecular target of SPIO nanoparticles mediated cancer-specific cytotoxicity. Biomaterials. 2016;83:102-114. (IF=10.273, JCR1区)

3.Fengkai Ruan, Rong Liu, Jie Zeng, Kai Wang, Zhenghong Zuo, Chengyong He*, Yongxing Zhang*, Cytotoxicity of black phosphorus quantum dots on lung-derived cells and the underlying mechanisms. Journal of Hazardous Materials. Accepted(IF=7.65, JCR1区)

4.Shengwei Jiang#, Yuchun Lin#, Huan Yao#, Chuanli Yang, Liyin Zhang, Bing Luo, Zhao Lei, Liwei Cao, Naibo Lin, Xiangyang Liu*, Zhongning Lin*, Chengyong He*. The role of unfolded protein response and ER-phagy in quantum dots-induced nephrotoxicity: an in vitro and in vivo study. Archives of Toxicology. 2018;92(541) 1-14. (IF=5.741, JCR1区)

5.Chengyong He#, Shengwei Jiang#, Huan Yao#, Liyin Zhang, Chuanli Yang, Denglin Zhan, Gan Lin, Yun Zeng, Yankai Xia, Zhongning Lin*, Gang Liu*, Yuchun Lin*. Endoplasmic reticulum stress mediates inflammatory response triggered by ultra-small superparamagnetic iron oxide nanoparticles in hepatocytes. Nanotoxicology. 2018;12(10): 1198-1214. (IF=5.955, JCR1区)

6.Chengyong He#, Shengwei Jiang#, Huan Yao#, Liyin Zhang, Chuanli Yang, Shan Jiang, Fengkai Ruan, Denglin Zhan, Gang Liu, Zhongning Lin*, Yuchun Lin*, Xiaoyuan Chen. High-content analysis for mitophagy response to nanoparticles: A potential sensitive biomarker for nanosafety assessment. Nanomedicine. 2019 Jan;15(1):59-69. (IF=5.57, JCR1区)

7.Mei Chen#, Shuzhen Chen#, Chengyong He#, Shiguang Mo, Xiaoyong Wang, Gang Liu*, and Nanfeng Zheng*, Safety profile of two-dimensional Pd nanosheets for photothermal therapy and photoacoustic imaging. Nano Research. 2017;10(4): 1234–1248. (IF=8.515, JCR1区)

8.Chengyong He#, Yang Qiu#, Peiyu Han#, Yuanyuan Chen, Liyin Zhang, Quan Yuan, Tianying Zhang, Tong Cheng, Lunzhi Yuan, Chenghao Huang, Sheng Zhang, Zhenyu Yin, Xian-E Peng, Dong Liang, Xu Lin, Yuchun Lin*, Zhongning Lin*, and Ningshao Xia. ER stress regulating protein phosphatase 2A-B56γ, targeted by hepatitis B virus X protein, induces cell cycle arrest and apoptosis of hepatocytes. Cell Death & Disease. 2018. Jul 9;9(7):762. (IF= 5.959, JCR2区)

9.Bing Luo#, Yuchun Lin#, Shengwei Jiang, Lianyun Huang, Huan Yao, Qunying Zhuang, Ran Zhao, Hengchuan Liu, Chengyong He*, Zhongning Lin*. Endoplasmic reticulum stress eIF2α-ATF4 pathway-mediated cyclooxygenase-2 induction regulates cadmium-induced autophagy in kidney. Cell Death & Disease. 2016;7: e2251; doi:10.1038/cddis.2016.78. (IF= 5.959, JCR2区)

10.Chuanli Yang, Peiyu Han, Fengkai Ruan, Tengjian Zhou, Bing Luo, Yang Qiu, Yuchun Lin, Zhongning Lin*, Chengyong He*. Lactational exposure to environmentally relevant benzo(a)pyrene causes astrocytic activation and anxiety-like behavior in male mice. Chemosphere. 2019.221: 67e74. (IF=5.108, JCR2区)

  

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