题 目：Bacterial natural products: understanding biosynthesis and biological activity
主讲人：Dr. Andrew Truman
Project Leader, John Innes Centre, UK
时 间：3月28日（周四），10:00~11:00 am
地 点：澳门新葡亰网站注册 E307学术报告厅
Microorganisms have provided humankind with a vast array of natural products with invaluable applications in medicine and agriculture. The advent of widespread genome sequencing has shown that bacteria actually have the genetic potential to make many more of these compounds. My group use a mixture of chemistry and genetics to elucidate biosynthetic pathways to known natural products and to “mine” into bacterial genomes to discover new natural products. This has enabled the characterisation of the biosynthetic pathways for multiple compounds with antibacterial and anticancer activities, as well as the genomics-guided discovery of anti-cancer compounds.